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Sinclair Method Studies

Published on: 11/06/2025

This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.

Alcohol Recovery – Time for Change

Alcohol Recovery – Time for Change

Published on: 20/02/2025

For decades, alcohol recovery has been dominated by traditional methods such as Alcoholics Anonymous (AA), Cocaine Anonymous (CA), Narcotics Anonymous (NA), and rehab programmes. While these approaches have helped some, they often rely on abstinence-based models, which can be challenging for many individuals.

The Sinclair Method (TSM)
Naltrexone Prescription and Support: How to Access Professional Help

Naltrexone Prescription and Support: How to Access Professional Help

Published on: 29/01/2025

Naltrexone is a medication widely used to help individuals reduce their alcohol intake. It works by blocking the brain's opioid receptors, reducing the pleasurable effects of alcohol and, over time, lowering cravings. Unlike abstinence-based treatments, Naltrexone is commonly used within The Sinclair Method (TSM), which allows individuals to continue drinking while gradually reducing their consumption.

The Sinclair Method (TSM)
Do I Take Naltrexone for Life on The Sinclair Method?

Do I Take Naltrexone for Life on The Sinclair Method?

Published on: 01/07/2024

Do I need to take Naltrexone for life when I am on The Sinclair Method?

Naltrexone Explained
Does The Sinclair Method Work?

Does The Sinclair Method Work?

Published on: 29/05/2024

The Sinclair Method (TSM) is a medication-based treatment for alcohol use disorder (AUD) that involves taking naltrexone, an opioid antagonist, before drinking. This method was developed by Dr John David Sinclair and aims to reduce the pleasurable effects of alcohol, thereby helping individuals cut down or quit drinking over time.

Success on The Sinclair Method
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